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Broad InstituteBroad Institute is a multidisciplinary community of researchers on a mission to improve human health.Broad Institute Skip to main content Top menu Careers Giving Intranet Search Show results from www.broadinstitute.orgintranet.broadinstitute.orgAll About usThis is Broad Learn about our mission, our values, our history, and partner institutions.People Meet our members, staff scientists, fellows, leadership, and other Broadies.Join Broad Find out how to join the Broad as an employee or associate member.Contact us Find our contact information, directions to our buildings, and directory.Broad@20 Broad turns 20 this year! See how we’re celebrating our 20th anniversary.ResearchDisease areas Broad brings people together to advance the understanding and treatment of disease.Items Wpapp colCancerCardiovascular diseaseBrain HealthDiabetesInfectious disease and microbiomeKidney diseaseObesityRare diseaseResearch areas Through programs spanning genetics, biology, and therapeutic development, Broad researchers are making discoveries that drive biomedical science forward.Items Wpapp colChemical biology and therapeutics scienceDrug discoveryGenome regulation, cellular circuitry, and epigenomicsImmunologyMedical and population geneticsMetabolismTechnology areas Our researchers use their expertise in creating, adapting, and applying a variety of technologies to enable science here and beyond.Items Wpapp colData sciencesGenetic perturbationGenomicsImagingMetabolomicsProteomicsSpatial technologiesSciencePatient-partnered research Patients partner with our scientists to accelerate the pace of discovery and find better treatments.Partnering and licensing We work closely with pharmaceutical, biotech, and technology partners to accelerate the translation of our discoveries.Publications A catalog of scientific papers published by our members and staff scientists.Resources, services, and tools Key scientific datasets and computational tools developed by our scientists and their collaborators.Collaborations and consortia We join with institutions and scientists the world over to address foundational challenges in science and health.CentersCarlos Slim Center for Health Research The Slim Center aims to bring the benefits of genomics-driven medicine to Latin America, gleaning new insights into diseases with relevance to the region.Gerstner Center for Cancer Diagnostics The Gerstner Center is developing next-generation diagnostic technology for cancer detection and tracking disease progression.Klarman Cell Observatory The Klarman Cell Observatory is systematically defining mammalian cellular circuits, how they work together to create tissues and organs, and are perturbed to cause disease.Merkin Institute for Transformative Technologies in Healthcare The Merkin Institute is supporting early-stage ideas aimed at advancing powerful technological approaches for improving how we understand and treat disease.Novo Nordisk Foundation Center for Genomic Mechanisms of Disease This center is developing new paradigms and technologies to scale the discovery of biological mechanisms of common, complex diseases, by facilitating close collaborations between the Broad Institute and the Danish research community.Eric and Wendy Schmidt Center The EWSC is catalyzing a new field of interdisciplinary research at the intersection of data science and life science, aimed at improving human health.Stanley Center for Psychiatric Research The Stanley Center aims to reduce the burden of serious mental illness by contributing new insights into pathogenesis, identifying biomarkers, and paving the way toward new treatments.Education and outreachArt and science connection Explore the connection between art and science and how we bring together artists and Broad scientists through our artist-in-residence program, gallery exhibitions, and ongoing public conversations.Broad Discovery Center Visit our free public educational space that showcases how researchers at the Broad and their colleagues around the world seek to understand and treat human disease. Learning resources Access free classroom materials and more for STEM educators, parents, students, tutors, and others. Public programs Discover remarkable stories of scientific progress, and explore the intersections of science, medicine, and society.Student opportunities Learn about Broad Institute's mentored research offerings for high school students, college students, and recent college graduates.Visit Broad Come see what Broad is all about.NewsNews and insights Learn about breakthroughs from Broad scientists.ColumnPress room Contact our media relations team.ColumnSign up for our newsletter Receive regular updates on Broad news, research and community.CareersGivingIntranetSearch Watch now Broad is accelerating discovery Broad Institute is a multidisciplinary community of researchers on a mission to improve human health. About us Latest News 09.05.2024 Q&A: Single-cell and spatial proteomics reveal proteins’ nuanced roles in health and disease Steve Carr and Claudia Ctortecka of the Proteomics Platform discuss recent advances from their group that can spur new research and the kinds of collaborations they are looking forward to. News 08.20.2024 #WhyIScience Q&A: A systems biologist develops computational tools to bring scale to cell experiments News 08.19.2024 A common fatty acid may help restore healthy vaginal bacteria after infection News 08.07.2024 Machine learning approach helps researchers design better gene-delivery vehicles for gene therapy All news Our community Join Broad We are a research organization dedicated to better understanding the roots of disease and narrowing the gap between new biological insights and impact for patients. Institute Members Associate and Affiliate Members Professional scientists Early career scientists Administration Affinity groups Partner institutions How we work Research Disease areas Research areas Technology areas Cancer Our scientists are probing the mechanisms of cancer and applying this knowledge to enable precision cancer medicine. /cancer Cardiovascular disease By applying a variety of tools and technologies, researchers here are working to reduce the burden of cardiovascular disease. /cardiovascular-disease Diabetes Our researchers study the cellular roles and physiological impacts of genes associated with type 2 diabetes. /diabetes Infectious disease and the microbiome Researchers across the institute are working to understand infectious diseases, antibiotic resistance, and the human microbiome. /infectious-disease-microbiome Kidney disease Our scientists are cataloging the molecular causes of kidney diseases in order to develop mechanism-based treatments. /kidney-disease Obesity By studying the genetic determinants of body weight, our researchers work to identify targets for future obesity therapies. /obesity Psychiatric disorders We are committed to characterizing psychiatric disorders' molecular roots and turning new findings into new treatments. /brain-health Rare disease Our scientists search for the risk factors underlying rare genetic diseases to help reveal their biological underpinnings and improve patients' lives. /rare-disease Previous Next Cancer Cardiovascular disease Diabetes Infectious disease and the microbiome Kidney disease Obesity Psychiatric disorders Rare disease Chemical biology and therapeutics science We are fostering a diverse research community engaged in innovative chemical biology and therapeutic research. /chemical-biology-and-therapeutics-science Drug discovery Our Center for the Development of Therapeutics (CDoT) helps scientists advance biological insights to new treatments. /center-development-therapeutics-cdot Genome regulation, cellular circuitry, and epigenomics Our scientists are charting the vast landscape of molecular elements that define and regulate the cell. /genomeregulation-cellcircuitry-epigenomics Immunology Researchers across Broad are defining the immune cells and pathways that regulate physiologic and pathologic processes. /immunology Medical and population genetics An array of scientists here are collaborating to establish genomic variations' roles in human traits and disorders. /medical-population-genetics Metabolism Our researchers aim to decipher the metabolic basis of rare and common human diseases. /metabolism Previous Next Chemical biology and therapeutics science Drug discovery Genome regulation, cellular circuitry, and epigenomics Immunology Medical and population genetics Metabolism Data sciences Members of the Data Sciences Platform build open-source technologies that help researchers everywhere connect to the patients, datasets, and tools they need to do life-changing science. /data-sciences Genetic perturbation The Genetic Perturbation Platform drives the functional study of the genome by developing groundbreaking technologies for perturbing genes at scale. /genetic-perturbation-platform Genomics Genomic scientists here at Broad create foundational resources and study the genomic basis of human traits and diseases. /genomics Imaging Computationally mining cellular images' rich information content can propel discoveries in biology and medicine. /imaging Metabolomics Cells' metabolites reveal unique chemical fingerprints of both normal and pathological disease processes. /metabolomics Proteomics Broad proteomic researchers address important questions in biology, chemistry, and clinical science through collaboration and technology development. /proteomics Previous Next Data sciences Genetic perturbation Genomics Imaging Metabolomics Proteomics Broad Discovery Series: Moving from "hit-or-miss" toward a brighter future for psychiatric diagnosis and care See what advocates, peers, and scientists had to say during a discussion of the past and future of psychiatric diagnosis care. Visit the Broad Discovery Center Explore exhibits showcasing how scientists are advancing our understanding of disease. The museum is in the ground floor atrium of the Merkin building at 415 Main Street, Cambridge, MA and is free and open to the public. Learn about summer research programs for students Watch a video to see how high school and undergraduate students have benefitted from doing summer research at Broad. Broad@20 Broad turns 20 this year! See how we’re celebrating our 20th anniversary. Address Merkin Building 415 Main St. Cambridge, MA 02142 Follow Us Twitter Facebook YouTube Instagram Linkedin Threads Sign up for our newsletter Name Did you know? In March of 2020, Broad Institute converted a clinical genetics processing lab into a large-scale COVID-19 testing facility in less than two weeks. We've screened more than 1,275 cancer cell lines as part of the Cancer Dependency Map (DepMap). Broad Genomics Platform sequences a whole human genome every four minutes. More than 11,000 individuals living with cancer in the United States and Canada have partnered with Count Me In to share their experiences and help accelerate cancer research. The Drug Repurposing Hub is one of the most comprehensive and up-to-date biologically annotated collections of FDA-approved compounds in the world. Researchers anywhere can explore more than 6,000 drugs in the hub and search for possible new uses for them to jump-start new drug discovery. In 2021, our sustainability efforts sent more than 80 percent of waste from the Genomics Platform to either a recycling facility or to an incineration plant that generates electricity. Through Broad's Scientists in the Classroom program, Broad researchers visit every 8th grade classroom in Cambridge each year to talk about genetics and evolution. Every summer, 18 high school students spend six weeks at Broad working side-by-side with mentors on cutting-edge research. In November 2022, Broad’s Genomics Platform sequenced its 500,000th whole human genome, a mere four years after sequencing its 100,000th. By the end of 2022, Broad’s COVID-19 testing lab had processed more than 37 million tests. Working with Addgene, Broad Institute has shared CRISPR genome-editing reagents with researchers at more than 3,200 institutions in 76 countries. The NeuroGAP-Psychosis project, a collaboration between the Stanley Center for Psychiatric Research and Harvard T.H. Chan School of Public Health to study the genetics of severe mental illness, has recruited more than 42,000 participants in Ethiopia, Kenya, Uganda, and South Africa. Previous Next Footer menu Report a concern Contact Us Privacy Policy © Broad Institute 2024 Please ensure Javascript is enabled for purposes of website accessibilityenen1727286652https://broadinstitute.org

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