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Cancer Research and TreatmentCancer Research and Treatment Skip Navigation Skip to contents Search Advanced Search ABOUT Aims and scope About the journal Editorial board Open access Best reviewer awardees Article processing charge Editorial office ToC Alerts BROWSE ARTICLES All issues Accepted articles Epub ahead-of print articles Current issue Most read articles Most cited articles Search Metrics FOR AUTHORS AND REVIEWERS Instructions for authors Research and publication ethics Checklist E-submission Copyright transfer agreement KCA Contact us E-SUBMISSION mobile search button mobile menu button ABOUT Aims and scope About the journal Editorial board Open access Best reviewer awardees Article processing charge Editorial office ToC Alerts BROWSE ARTICLES All issues Accepted articles Epub ahead-of print articles Current issue Most read articles Most cited articles Search Metrics FOR AUTHORS AND REVIEWERS Instructions for authors Research and publication ethics Checklist E-submission Copyright transfer agreement Current Issue  Volume 58(1); January 2026 PREVIOUS ALL ISSUES Review ArticleDecember 26, 2025 Diagnostic Challenges and Clinical Implications of Microsatellite Instability/Mismatch Repair Deficiency in Solid Tumors Yoonjin Kwak, Jeong Mo Bae, Hye Seung Lee Cancer Res Treat. 2026;58(1):1-14. Published online December 26, 2025 Review ArticleDecember 18, 2025 Redefining HER2 in Breast Cancer: From Conventional Positivity to Low and Ultralow in the New Era of Antibody-Drug Conjugates Jiwon Koh, Seock-Ah Im Cancer Res Treat. 2026;58(1):15-25. Published online December 18, 2025 Review ArticleApril 29, 2025 Understanding Immune Cell Adaptation to Tumor Hypoxia for Maximized Therapeutic Efficacy of Immunotherapy: Biology and Non-invasive Imaging Application Taerim Oh, Minwoo Kim, Gi-Sue Kang, Sung-Joon Ye, Changhoon Choi, et al. Cancer Res Treat. 2026;58(1):26-47. Published online April 29, 2025 Original ArticleMarch 27, 2025 Association of Physical Activity with Dementia Risk in Cancer Survivors: A Korean Nationwide Cohort Study Su Kyoung Lee, Minji Han, Sangwoo Park, Sun Jae Park, Jihun Song, et al. Cancer Res Treat. 2026;58(1):48-60. Published online March 27, 2025 Original ArticleFebruary 12, 2025 Long-term Immunogenicity of the 13-valent Pneumococcal Conjugate Vaccine during Adjuvant Chemotherapy in Patients with Gastric and Colorectal Cancer: A 5-Year Follow-up of a Randomized Controlled Trial Hyeon-Jong Kim, Hyunjin Bang, Hyun-Jung Shim, Jun Eul Hwang, Sang-Hee Cho, et al. Cancer Res Treat. 2026;58(1):61-70. Published online February 12, 2025 Original ArticleMarch 10, 2025 Elevated SLC3A2 Expression Promotes the Progression of Gliomas and Enhances Ferroptosis Resistance through the AKT/NRF2/GPX4 Axis Yuqian Zheng, Shaolong Zhou, Yiran Tao, Zimin Shi, Xiang Li, et al. Cancer Res Treat. 2026;58(1):71-94. Published online March 10, 2025 Original ArticleApril 10, 2025 Reduced Dose and Selective Neck Irradiation Policy in Treating Oropharynx Cancer: Excellent Oncological Outcomes with Very Low Risk of Locoregional Failure Eunyeong Yang, Seung Gyu Park, Kyungmi Yang, Dongryul Oh, Yong Chan Ahn Cancer Res Treat. 2026;58(1):95-106. Published online April 10, 2025 Original ArticleFebruary 26, 2025 Novel Bronchoscopy Method for Molecular Profiling of Lung Cancer: Targeted Washing Technique Mi-Hyun Kim, Hayoung Seong, Hyojin Jang, Saerom Kim, Wanho Yoo, et al. Cancer Res Treat. 2026;58(1):107-114. Published online February 26, 2025 Original ArticleMarch 4, 2025 The Profile of Gut Microbiota in Carcinogenesis Driven by Mutant EGFR in Non–Small Cell Lung Cancer Da-Som Kim, Eun Hye Kim, Ji Yong Kim, Dong Ha Kim, Yun Jung Choi, et al. Cancer Res Treat. 2026;58(1):115-127. Published online March 4, 2025 Original ArticleMarch 27, 2025 The Role of Circulating Tumor Cell as a Promising Biomarker in the Evaluation of Pulmonary Nodules: A Prospective Study Shijie Wang, Changdan Xu, Xiaohong Xu, Weipeng Shao, Guohui Wang, et al. Cancer Res Treat. 2026;58(1):128-140. Published online March 27, 2025 Original ArticleFebruary 26, 2025 Association between Benign Thyroid Disorders and Breast Cancer Risk in Korean Women Boyoung Park, Thi Xuan Mai Tran Cancer Res Treat. 2026;58(1):141-150. Published online February 26, 2025 Original ArticleMarch 5, 2025 Ten-Year Follow-up Clinical Outcomes and the Role of Adjuvant Chemotherapy in HER2-Positive Patients with Microinvasive Breast Cancer Yeokyeong Shin, Soo-Young Lee, Hyehyun Jeong, Jin-Hee Ahn, Kyung Hae Jung, et al. Cancer Res Treat. 2026;58(1):151-158. Published online March 5, 2025 Original ArticleApril 7, 2025 Elimusertib, a Novel ATR Inhibitor, Induces Anti-tumor Effects through Replication Catastrophe in Breast Cancers Mudong Kim, Ahrum Min, Sohyeon Kim, Seongyeong Kim, Yu-jin Kim, et al. Cancer Res Treat. 2026;58(1):159-174. Published online April 7, 2025 Original ArticleApril 15, 2025 Comparison of Long-term Oncological Outcome of Sentinel Lymph Node Mapping Methods (Dye-Only versus Dye and Radioisotope) in Breast Cancer Patients Following Neoadjuvant Chemotherapy Jinyoung Byeon, Changjin Lim, Eunhye Kang, Ji-Jung Jung, Hong-Kyu Kim, et al. Cancer Res Treat. 2026;58(1):175-181. Published online April 15, 2025 Original ArticleApril 15, 2025 Spatial Transcriptomic Landscape of Brain Metastases from Triple-Negative Breast Cancer: Comparison of Primary Tumor and Brain Metastases Using Spatial Analysis Jihwan Yoo, Inho Park, Hyun Jung Kim, Hun Ho Park, Sora Lee, et al. Cancer Res Treat. 2026;58(1):182-197. Published online April 15, 2025 Original ArticleApril 15, 2025 The Impact of Obesity on Treatment Outcomes in Patients with Hormone Receptor–Positive HER2-Negative Metastatic Breast Cancer Receiving CDK 4/6 Inhibitors Yoo Bin Jung, Hee Kyung Ahn, Hyun-Young Shin, Ji Hyung Hong, Chai Hong Rim Cancer Res Treat. 2026;58(1):198-207. Published online April 15, 2025 Original ArticleApril 24, 2025 Adjuvant Chemotherapy in Breast Cancer after Neoadjuvant Therapy: Essential or Optional? Di Zhang, Luo Yang, Yuan Zheng, Qi Zhou Cancer Res Treat. 2026;58(1):208-220. Published online April 24, 2025 Original ArticleMarch 5, 2025 Detection Ability of Quality of Life Changes and Responsiveness of the KOQUSS-40 and the EORTC QLQ-C30/STO22 in Patients Who Underwent Gastrectomy: A Prospective Comparative Study Bang Wool Eom, Keun Won Ryu, Ji Yeong An, Yun-Suhk Suh, In Cho, et al. Cancer Res Treat. 2026;58(1):221-231. Published online March 5, 2025 Original ArticleApril 1, 2025 The Effect of Alcohol Consumption Behavior Changes on Gastric Cancer Risks Stratified by Sex in South Korea Yonghoon Choi, Jieun Jang, Hyeong Ho Jo, Nayoung Kim Cancer Res Treat. 2026;58(1):232-241. Published online April 1, 2025 Original ArticleApril 18, 2025 Deciphering the Risk of Developing Lung Cancer after the Diagnosis of Gastric Cancer with Genetic Evidence: A European and East Asian Populations–Based Mendelian Randomization Analysis Jiansheng Chen, Aiming Zeng, Yunzhe Yu, Sida Sun, Liqun Liao, et al. Cancer Res Treat. 2026;58(1):242-251. Published online April 18, 2025 Original ArticleApril 16, 2025 Survival Rates of Patients with Gastric Cancer According to Age and Sex: A Large-Scale Study Using Data from 14,739 Patients Yonghoon Choi, Nayoung Kim, Ji Hyun Kim, Hyeong Ho Jo, Hyeon Jeong Oh, et al. Cancer Res Treat. 2026;58(1):252-263. Published online April 16, 2025 Original ArticleFebruary 18, 2025 Molecular Mosaics: Unveiling Heterogeneity in Synchronous Colorectal Cancers Hyun Gu Lee, Yeseul Kim, Mi-Ju Kim, Yeon Wook Kim, Sun-Young Jun, et al. Cancer Res Treat. 2026;58(1):264-274. Published online February 18, 2025 Original ArticleMay 22, 2025 Combined Transarterial Chemoembolization and External Beam Radiotherapy for Identifying Surgical Candidates for Hepatocellular Carcinoma with Macroscopic Vascular Invasion: A Propensity Score–Weighted Analysis Sumin Lee, Jinhong Jung, Jonggi Choi, So Yeon Kim, Jin Hyoung Kim, et al. Cancer Res Treat. 2026;58(1):275-283. Published online May 22, 2025 Original ArticleFebruary 13, 2025 A Multicenter Phase II Study of Modified FOLFIRINOX for First-Line Treatment for Advanced Urachal Cancer (ULTIMA; KCSG GU20-03) Inkeun Park, Jae Lyun Lee, Shinkyo Yoon, Sang Joon Shin, Seong-Hoon Shin, et al. Cancer Res Treat. 2026;58(1):284-291. Published online February 13, 2025 Original ArticleMarch 19, 2025 Efficacy of Chemotherapy Following Prior PARP-Inhibitor Treatment in Patients with Ovarian Cancer Jung Chul Kim, Junsik Park, Yong Jae Lee, Eun Ji Nam, Sang Wun Kim, et al. Cancer Res Treat. 2026;58(1):292-299. Published online March 19, 2025 Original ArticleApril 15, 2025 Cost-Effectiveness Analysis of Daratumumab Monotherapy and Subsequent Therapies in Heavily Treated Relapsed/Refractory Multiple Myeloma: A Feasible Methodology using a Korean Nationwide Population Cohort Sung-Soo Park, Suein Choi, Seungpil Jung, Seunghoon Han, Chaehyeon Lee, et al. Cancer Res Treat. 2026;58(1):300-310. Published online April 15, 2025 Original ArticleFebruary 21, 2025 Validating the Korean Geriatric Assessment Tool in Elderly Multiple Myeloma Patients: A Multicenter Study Ji Yun Lee, Sang-A Kim, Youngil Koh, Ho-Young Yhim, Gyeong-Won Lee, et al. Cancer Res Treat. 2026;58(1):311-319. Published online February 21, 2025 Original ArticleApril 25, 2025 Real-World Experience of Weekly Carfilzomib in Combination with Cyclophosphamide and Dexamethasone in Multiple Myeloma Relapsed/Refractory to Bortezomib and Lenalidomide Cheongin Yang, Changgon Kim, Kunye Kwak, Ka-Won Kang, Yong Park, et al. Cancer Res Treat. 2026;58(1):320-328. Published online April 25, 2025 Original ArticleMarch 12, 2025 Pilot Study for Feasibility of Onco-Geriatric Intervention Model in Older Patients with Cancer in a Tertiary Academic Hospital Jin Won Kim, Jung-Yeon Choi, Woochan Park, Minsu Kang, Jeongmin Seo, et al. Cancer Res Treat. 2026;58(1):329-338. Published online March 12, 2025 Original ArticleApril 10, 2025 Exploring Oncologists’ Perspectives on the Early Integration of Specialty Palliative Care in Korea: Challenges, Needs, and Clinical Implications Shin Hye Yoo, Yu Jung Kim, Ye Sul Jeung, Jung Sun Kim, Kwonoh Park, et al. Cancer Res Treat. 2026;58(1):339-348. Published online April 10, 2025 prev next Review Article Diagnostic Challenges and Clinical Implications of Microsatellite Instability/Mismatch Repair Deficiency in Solid Tumors Yoonjin Kwak, Jeong Mo Bae, Hye Seung Lee Cancer Res Treat. 2026;58(1):1-14. Published online December 26, 2025 Review Article Redefining HER2 in Breast Cancer: From Conventional Positivity to Low and Ultralow in the New Era of Antibody-Drug Conjugates Jiwon Koh, Seock-Ah Im Cancer Res Treat. 2026;58(1):15-25. Published online December 18, 2025 Review Article Understanding Immune Cell Adaptation to Tumor Hypoxia for Maximized Therapeutic Efficacy of Immunotherapy: Biology and Non-invasive Imaging Application Taerim Oh, Minwoo Kim, Gi-Sue Kang, et al. Cancer Res Treat. 2026;58(1):26-47. Published online April 29, 2025 Original Article Association of Physical Activity with Dementia Risk in Cancer Survivors: A Korean Nationwide Cohort Study Su Kyoung Lee, Minji Han, Sangwoo Park, et al. Cancer Res Treat. 2026;58(1):48-60. Published online March 27, 2025 Original Article Long-term Immunogenicity of the 13-valent Pneumococcal Conjugate Vaccine during Adjuvant Chemotherapy in Patients with Gastric and Colorectal Cancer: A 5-Year Follow-up of a Randomized Controlled Trial Hyeon-Jong Kim, Hyunjin Bang, Hyun-Jung Shim, et al. Cancer Res Treat. 2026;58(1):61-70. Published online February 12, 2025 Original Article Elevated SLC3A2 Expression Promotes the Progression of Gliomas and Enhances Ferroptosis Resistance through the AKT/NRF2/GPX4 Axis Yuqian Zheng, Shaolong Zhou, Yiran Tao, et al. Cancer Res Treat. 2026;58(1):71-94. Published online March 10, 2025 Original Article Reduced Dose and Selective Neck Irradiation Policy in Treating Oropharynx Cancer: Excellent Oncological Outcomes with Very Low Risk of Locoregional Failure Eunyeong Yang, Seung Gyu Park, Kyungmi Yang, et al. Cancer Res Treat. 2026;58(1):95-106. Published online April 10, 2025 Original Article Novel Bronchoscopy Method for Molecular Profiling of Lung Cancer: Targeted Washing Technique Mi-Hyun Kim, Hayoung Seong, Hyojin Jang, et al. Cancer Res Treat. 2026;58(1):107-114. Published online February 26, 2025 VIEW MORE Epub Ahead-of Print Articles Keratin 6A Overexpression in the Lymphovascular Invasion–Associated Tumor Subgroup Promotes Progression of Triple-Negative Breast Cancer Wei Luo, Yiping Zou, Yantao Jiang, et al. Comparative Effectiveness of Anbalcabtagene Autoleucel versus Tisagenlecleucel in Patients with Relapsed/Refractory Diffuse Large B-Cell Lymphoma Hee-Jin Seo, Woo Hyeon Yoo, Kyungyeon Jung, et al. Barriers to Clinical Trial Enrollment: KCSG Survey–Based Perspectives of Medical Oncologists, Patients, and Their Caregivers Chi Hoon Maeng, Inkeun Park, In Hee Lee, et al. HER3 Expression and PIK3CA Mutational Status Predict Pathological Response of Neoadjuvant Therapy in HER2-Positive Breast Cancer Patients Xi Xia, Zhiqiang Zong, Jian Shen, et al. Nivolumab Plus Chemotherapy Versus Placebo Plus Chemotherapy in Korean Patients with HER2-Negative, Untreated, Unresectable Advanced or Recurrent Gastric or Gastroesophageal Junction Cancer: Subgroup Analysis of a Randomized, Multicenter, Double-Blind Phase 3 Trial (ATTRACTION-4) Yoon-Koo Kang, Min-Hee Ryu, Do-Youn Oh, et al. VIEW MORE Accepted Articles A Novel Classification of Esophageal Anastomotic Leaks and Its Impact on Healing Time After Esophagogastrostomy Zhao Ma, Jie Zheng, Hongbo Wang, et al. Associations between Smoking, Opioid Analgesic Use, and Risk For Chemical Coping in Korean Patients with Advanced Cancer Eun Hee Jung, Yu Jung Kim, Rony Dev, et al. Safety and Efficacy of Combining Metastasis-Directed Stereotactic Ablative Radiation Therapy with Tyrosine Kinase Inhibitors Versus Immune Checkpoint Inhibitors in Metastatic Hepatocellular Carcinoma Eunyeong Yang, Jeong Il Yu, Hee Chul Park, et al. Postoperative Radiotherapy May Improve Survival in Certain Patients with pN2 Non-Small Cell Lung Cancer Who Do Not Have Extranodal Extension Seung Hyuck Jeon, Changhoon Song, Jae Hyun Jeon, et al. Biomarker Testing Practices for Non-small Cell Lung Cancer: Survey Insights from South Korean Pathology Laboratories Sehui Kim, Dajeong Kim, Lucia Kim, et al. VIEW MORE MOST VIEWED Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 202118,346 HER2-Low Breast Cancer: Now and in the Future18,329 Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 202215,876 Editor’s Note on Recent Journal Impact Factor of Cancer Research and Treatment12,579 Prediction of Cancer Incidence and Mortality in Korea, 202512,336 VIEW MORE MOST CITED Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2021115 Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 202230 Prediction of Cancer Incidence and Mortality in Korea, 202425 Data Resource Profile: The Cancer Public Library Database in South Korea23 HER2-Low Breast Cancer: Now and in the Future23 VIEW MORE ARCHIVE pISSN 1598-2998    eISSN 2005-9256 The official journal of Korean Cancer Association Korean Society of Medical Oncology Korean Association for Lung Cancer E-Submission Submit Your Manuscript ABOUT Aims and scope About the journal Editorial board Open access Best reviewer awardees Article processing charge Editorial office ToC Alerts BROWSE ARTICLES  All issues Accepted articles Epub ahead-of print articles Current issue Most read articles Most cited articles Search Metrics FOR AUTHORS AND REVIEWERS  Instructions for authors Research and publication ethics Checklist E-submission Copyright transfer agreement © Korean Cancer Association. 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