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Signa VitaeJournal of Anesthesiology, British Anesthesiology, American Journal of Anesthesiology, Pediatric Anesthesiology, Signa Vitae, 1334-5605Signa Vitae is an international peer-reviewed open access journal, which is currently indexed in SCIE, scopus, etc. It covers many aspects of adult, pediatric and neonatal intensive care, anesthesia and emergency medicineSigna Vitae MRE Press Home Journals European Journal of Gynaecological OncologyJournal of Clinical Pediatric DentistryJournal of Men's HealthJournal of Oral & Facial Pain and HeadacheRevista Internacional de AndrologíaSigna VitaeAbout OverviewManagement TeamContactResources For AuthorsFor ReviewersFor EditorsArticle Processing ChargesOpen AccessEditorial policiesPublishing EthicCopyright & LicenseDigital ArchivePrivacy PolicyAdvertising policyPeer Review PolicySpecial Issues & Supplements PolicyNews Home Journal Info OverviewAims & ScopeEditorial BoardIndexing & ArchivingJoin Editorial BoardSpecial Issues Special IssuesEdit a Special IssueArticles Current IssueArchivePublished Ahead of Print For Authors SubmitInstructions for AuthorsArticle Processing ChargeEditorial ProcessContact Us Article Sepcial Issue Advanced Title Author DOI Article Type ALL Special Issue ALL Volume ALL Issue ALL Search Signa VitaePrint ISSN: 1334-5605 | Online ISSN: 1845-206XSigna Vitae (SV) is a peer-reviewed, open-access journal that aims to be an unbiased and permanent forum for the fields of emergency medicine, intensive care medicine, anesthesia and pain medicine. It focuses on the latest research advances in these fields, including Disease prevention, diagnose, treatment and prognosis, Disease etiology, pathophysiology, and molecular mechanisms, Health care, Medical personnel health, Facilities and equipment, Teaching and training, Organization and management, Information and techniques, Drug application, etc. As a tool for easier and more effective experiences and science sharing, SV aims to provide professionals dedicated to all these relevant fields with cutting-edge techniques and information. Early postoperative cognitive decline—are there any preventive strategies for surgical patients in the emergency setting? Articles Latest Articles Most Read Open Access Effects of anesthesia and other perioperative factors on immune function: a narrative review Yining Chen,Junwei Kang,Yulang Wang,Xiongxiong Pan DOI: 10.22514/sv.2024.105 Abstract ( 525 ) PDF (3.4 MB) ( 116 ) Full TextOpen Access Non-steroidal anti-inflammatory drugs and postoperative atrial fibrillation in patients having non-cardiac surgery: a systematic review Nicoleta Ntalarizou,Nikolaos Papagiannakis,Eleni Laou,Konstantinos Ekmektzoglou,Nicoletta Iacovidou,Theodoros Xanthos,Athanasios Chalkias DOI: 10.22514/sv.2024.106 Abstract ( 894 ) PDF (983.39 kB) ( 145 ) Full TextOpen Access Comparing the predictive performance of in-hospital mortality of different frailty scales for elderly patients in the emergency department I-Wei Fan,Yu-Hsiang Chen,Wan-Ling Hsu,Chip-Jin Ng,Yi-Ming Weng DOI: 10.22514/sv.2024.107 Abstract ( 630 ) PDF (3.53 MB) ( 164 ) Full TextOpen Access A backboard makes manual chest compressions more effective on bed mattresses Aki Otsuka,Yoshifumi Kawakubo,Tomoyuki Tanaka,Masanobu Tsurumoto,Keisuke Hayashi,Takunori Shimazaki,Mana Kawakubo,Takashi Hitosugi,Takesh Yokoyama DOI: 10.22514/sv.2024.108 Abstract ( 492 ) PDF (2.06 MB) ( 121 ) Full TextOpen Access Effect of adjusting the positive end-expiratory pressure levels based on the driving pressure in elderly patients undergoing laparoscopic colorectal cancer surgery: a randomized controlled trial Yi Zheng,Juncheng Xiong,Qian Zhuo,Zonghuai Pan,Lvdan Huang DOI: 10.22514/sv.2024.109 Abstract ( 528 ) PDF (7.45 MB) ( 139 ) Full TextOpen Access Access to urgent care in Riyadh: a study of equity and personalization Ahmed M. Al-Wathinani,Afnan Alwasedi,Badriyah Almutairi,Reem Alqhatani,Maryam M. Zila,Manahel Alshaer,Musab A. Alharthi,Nawaf A. Albaqami,Krzysztof Goniewicz DOI: 10.22514/sv.2024.110 Abstract ( 517 ) PDF (197.88 kB) ( 156 ) Full TextOpen Access Cirsilineol reduces inflammation and apoptosis in an in vitro model of acute pancreatitis Wanqiong Zheng,Ye Tian,Yiming Zhang,Binnan Li DOI: 10.22514/sv.2024.111 Abstract ( 504 ) PDF (19.42 MB) ( 159 ) Full TextOpen Access Impact of inter-visit duration on mortality in older adults who use emergency department frequently Mehmet C. Demir,Kudret Selki,Erdinç Şengüldür DOI: 10.22514/sv.2024.112 Abstract ( 455 ) PDF (3.79 MB) ( 144 ) Full TextOpen Access Lorazepam attenuates neuroinflammation by suppressing T cell infiltration in diabetic peripheral neuropathy Ying Wang,Yaping Sui,Chunli Xing DOI: 10.22514/sv.2024.113 Abstract ( 490 ) PDF (15.85 MB) ( 146 ) Full TextOpen Access Inpatient falls in burn units Anna Chrapusta,Marcin Mikos,Agnieszka Surowiecka,Iwona Grzelak,Joanna Piszczek,Tomasz Korzeniowski,Jerzy Strużyna DOI: 10.22514/sv.2024.114 Abstract ( 443 ) PDF (817.13 kB) ( 149 ) Full TextOpen Access Study on the application effect of problem-based learning with situational simulation teaching method in cardiopulmonary resuscitation training Jie Yang,Meifang Wang,Shunjuan Xu,Yali Bian DOI: 10.22514/sv.2024.115 Abstract ( 455 ) PDF (183.78 kB) ( 123 ) Full TextOpen Access Global catastrophe of hospital disasters: a retrospective analysis (1976–2023) Zakaria A. Mani,Amir Khorram-Manesh,Hissah Alotaibi,Krzysztof Goniewicz DOI: 10.22514/sv.2024.092 Abstract ( 856 ) PDF (1.14 MB) ( 148 ) Full TextOpen Access Artesunate inhibits ROS production and ameliorates mitochondrial damage through the SIRT1/FOXO3a/MnSOD pathway to alleviate heart failure Yaping Li,Peng Hu DOI: 10.22514/sv.2024.116 Abstract ( 547 ) PDF (4.89 MB) ( 134 ) Full TextOpen Access Efficacy of using early multimodal vasopressor therapy on survival after septic shock in patients receiving high-dose norepinephrine: a retrospective study based on the MIMIC database Tingting Wang,Xiaohong Zhou,Peihao Yu,Jianqing Zhu,Qi Li,Xiaoling Yang DOI: 10.22514/sv.2024.117 Abstract ( 474 ) PDF (2.85 MB) ( 112 ) Full TextOpen Access Life-threatening hyperkalemia after excessive ingestion of boiling water with Jerusalem artichoke extract: case report Ji Ho Lee,Dong Hun Lee DOI: 10.22514/sv.2024.118 Abstract ( 408 ) PDF (1.1 MB) ( 125 ) Full Text all Published Ahead of Print Open Access Modified thoracoabdominal nerve block through perichondrial approach for laparoscopic appendectomy in children: a randomized trial Ela Erten,Gokhan Berktug Bahadır,Umut Kara,Fatih Simsek,Huseyin Emre Atasever,Seyyid Furkan Kına,Yasemin Ozkan Online publish date: 26 July 2024 DOI: 10.22514/sv.2024.093 Abstract ( 741 ) PDF (4.87 MB) ( 127 ) Full Text all Development of a real-time monitoring and detection indoor air quality system for intensive care unit and emergency department Special Issues Special issue title: Critical Interventions: Enhancing Emergency Medical Services through Interdisciplinary Research Keywords: Emergency Medical Services; Interdisciplinary Research in EMS; Pre-hospital Care Technologies; Crisis Management in Healthcare; Psychological Aspects of EMS; Public Health and Emergency Services Editor: Prof. Dr. Krzysztof Goniewicz, PhD,Prof. Dr. Ahmed M. Al-Wathinani, PhD Submission deadline: 28 February 2025Special issue title: AI Horizons: Revolutionizing Anesthesia, Critical Care, and Pain Medicine Keywords: Anesthesia; Critical Care Medicine; Pain Medicine; Artificial Intelligence; Large Language Models; Natural Language Processing; Big Data; Data Science; Machine Learning Editor: Prof. Marco Cascella Submission deadline: 31 December 2024Special issue title: Advances in Obstetric Anaesthesia Keywords: Obstetric Anaesthesia; Epidural Analgesia; Remifentanil-PCA; Labour and Delivery Outcomes; Quality Control in Perinatology and Obstetric Anaesthesia; ROTEM; Obstetric Haemorrhage; Preeclampsia Editor: Prof. Tatjana Stopar Pintarič, MD, PhD, DEAA Submission deadline: 31 December 2023Special issue title: Cardiothoracic anaesthesia and intensive care: current challenges and novelties Keywords: cardiac anaesthesia, thoracic anaesthesia, intensive care, education, innovation, perioperative medicine, healthcare, outcomes, challenges Editor: Dr. Marko Zdravkovic, MD, PhD Submission deadline: 30 November 2022Special issue title: Selected papers from Korean Society of Emergency Medicine (KSEM) in 2021-2022 Keywords: Emergency medicine Editor: Kyungwon Lee, MD, PhD,Young Duck Cho, MD, PhD Submission deadline: 31 December 2022Special issue title: Medical Simulation - success in education, future of science Keywords: medical simulation, emergency medicine, medical education Editor: Tomasz Kłosiewicz, MD, MSc,Mateusz Puślecki, PhD Submission deadline: 31 December 2022Special issue title: 21st Panhellenic Congress on Regional Anaesthesia, Pain Management and Palliative Care Keywords: Regional Anaesthesia, Pain Management, Palliative Care, PARH.SY.A., ESRA HELLAS, the A’ Anaesthesiology Department, Faculty of Medicine, University of Athens Editor: Dr. Ioanna Siafaka, MD, PhD,Dr. Maria Kokolaki, MD, PhD,Dr. Athina Vadalouca, MD, PhD, FIPP,Dr. Evmorfia Stavropoulou, MD, PhD, EDRA,Dr. Eleni Moka, MD, PhD, MSc, EDRA Submission deadline: 27 May 2022Special issue title: Selected papers from Korean Association of Cardiopulmonary Resuscitation in 2021 Keywords: Cardiac arrest, Resuscitation, cardiopulmonary resuscitation, guidelines, outcome Editor: Prof. Won Young Kim, MD, PhD Submission deadline: 01 June 2022Special issue title: Spinal Cord Injury Keywords: Spinal cord injury (SCI), Damage mechanisms, Primary and secondary medullary lesions, Neurorehabilitation, Neurorestoration Editor: Lecturer dr. Constantin Munteanu, PhD,Prof. Dr. Gelu Onose,Associate Prof. Dr. Mariana Rotariu, PhD,Assistant Prof. Dr. Gabriela Dogaru, PhD,Associate Prof. Dr. Elena Valentiana IONESCU, PhD,Assistant Prof. Dr. Cristina Daia, PhD Submission deadline: 31 March 2022Special issue title: Outcome Measures and Assessment Tools in Spinal Cord Injury Keywords: Spinal Cord Injury, Rehabilitation, Assessment Tools Editor: Dr. Giovanni Galeoto Submission deadline: 10 December 2021 all To Be a Reviewer If you would like to review a manuscript for Signa Vitae journal, please click “Review for SV” below to register at our submission website or log in our Online Peer Review system. Your name, contact details, and expertise will be automatically added to our database of reviewers. Review for SV Join Editorial Board You are welcome to join our editorial board. Our journal produces and issues editorial board certificates for editorial board members, and the journal website will display the names and personal websites of editorial board members to help enhance their scientific influence. Members of the editorial committee are entitled to 1 free publication (editorial member’s or recommended paper) per year, and other articles over 2 can enjoy 30% discount of publishing fee. Join Editorial Board Editor-in-ChiefProf. Giovanni Landoni, MDProf Giovanni Landoni, MD, is currently Full Professor and Residency Program Director of Anesthesia and Intensive Care Medicine at Vita-Salute San Raffaele University, Milan, Italy. He’s also Director of the Center for Intensive Care and Anesthesiology of San Raffaele Hospital in Milan, Italy. His strong clinical and research interests in intensive care and anesthesia resulted in more than 700 scientific publications in indexed journals, cited >20,000 times, h-index=75 on Scopus and 95 on Scholar, including randomized trials on NEJM, Lancet, and JAMA, and over 100 invitations in international congresses. He participated to 47 randomized controlled trials. Prof Landoni was Chief Investigator in successfully completed multicenter randomized clinical trials that randomized > 10,000 critically ill or perioperative patients over the last 10 years. He served as reviewer for over 50 journals (NEJM, JAMA, and The Lancet among others) and for foreign grant agencies, and he is member of the Editorial Board of several international journals. Current Issue Vol., Issue , Invalid date Table of contents All Issues Submit to SV Review for SV Edit a Special Issue Abstracted / indexed in Science Citation Index Expanded (SciSearch) Created as SCI in 1964, Science Citation Index Expanded now indexes over 9,200 of the world’s most impactful journals across 178 scientific disciplines. More than 53 million records and 1.18 billion cited references date back from 1900 to present. Journal Citation Reports/Science Edition Journal Citation Reports/Science Edition aims to evaluate a journal’s value from multiple perspectives including the journal impact factor, descriptive data about a journal’s open access content as well as contributing authors, and provide readers a transparent and publisher-neutral data & statistics information about the journal. Chemical Abstracts Service Source Index The CAS Source Index (CASSI) Search Tool is an online resource that can quickly identify or confirm journal titles and abbreviations for publications indexed by CAS since 1907, including serial and non-serial scientific and technical publications. Index Copernicus The Index Copernicus International (ICI) Journals database’s is an international indexation database of scientific journals. It covered international scientific journals which divided into general information, contents of individual issues, detailed bibliography (references) sections for every publication, as well as full texts of publications in the form of attached files (optional). For now, there are more than 58,000 scientific journals registered at ICI. Geneva Foundation for Medical Education and Research The Geneva Foundation for Medical Education and Research (GFMER) is a non-profit organization established in 2002 and it works in close collaboration with the World Health Organization (WHO). The overall objectives of the Foundation are to promote and develop health education and research programs. Scopus: CiteScore 1.3 (2023) Scopus is Elsevier's abstract and citation database launched in 2004. Scopus covers nearly 36,377 titles (22,794 active titles and 13,583 Inactive titles) from approximately 11,678 publishers, of which 34,346 are peer-reviewed journals in top-level subject fields: life sciences, social sciences, physical sciences and health sciences. 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